From the site:
PyWebOff is a compare-and-contrast exercise to evaluate the strengths and weaknesses of some of the major Python web application frameworks.Thank you! This is something that we Pythonistas really need.
So far, the answer to "how does Python support web programming?" has been "well, there's Zope, Webkit, CherryPy, Quixote, Woven..." There hasn't been much "If you want X, then you probably want Y." advice.
XML support in Python has the same issues. Maybe some disinterested party can do a similar analysis there.